crohnR Documentation

Crohn's disease data

Description

The data set consist of 103 common (>5% minor allele frequency) SNPs genotyped in 129 trios from an European-derived population. These SNPs are in a 500-kb region on human chromosome 5q31 implicated as containing a genetic risk factor for Crohn disease.

The positions, names and haplotype blocks reported are as follows,

274044   IGR1118a_1	BLOCK 1
274541   IGR1119a_1	*
286593   IGR1143a_1	*
287261   IGR1144a_1	*
299755   IGR1169a_2	*
324341   IGR1218a_2	*
324379   IGR1219a_2	*
358048   IGR1286a_1	BLOCK 1
366811	 TSC0101718
395079   IGR1373a_1	BLOCK 2
396353   IGR1371a_1	*
397334   IGR1369a_2	*
397381   IGR1369a_1	*
398352   IGR1367a_1	BLOCK 2
411823   IGR2008a_2
411873   IGR2008a_1	BLOCK 3
412456   IGR2010a_3	*
413233   IGR2011b_1	*
415579   IGR2016a_1	*
417617   IGR2020a_15	*
419845   IGR2025a_2	*
424283   IGR2033a_1	*
425376   IGR2036a_2	*
425549   IGR2036a_1	BLOCK 3
433467   IGR2052a_1	BLOCK 4
435282   IGR2055a_1	*
437682   IGR2060a_1	*
438883   IGR2063b_1	*
443565   IGR2072a_2	*
443750   IGR2073a_1	*
445337   IGR2076a_1	*
447791   IGR2081a_1	*
449895   IGR2085a_2	*
455246   IGR2096a_1	*
463136   IGR2111a_3	BLOCK 4
482171   IGR2150a_1	BLOCK 5
485828   IGR2157a_1	*
495082   IGR2175a_2	*
506266   IGR2198a_1	*
506890   IGR2199a_1	BLOCK 5
507208   IGR2200a_1	BLOCK 6
508338   IGR2202a_1	*
508858   IGR2203a_1	*
510951   IGR2207a_1	*
518478   IGR2222a_2	BLOCK 6
519387   IGR2224a_2	BLOCK 7
519962   IGR2225a_1	*
520521   IGR2226a_3	*
522600   IGR2230a_1	*
525243   IGR2236a_1	*	
529556   IGR2244a_4	*
532363   IGR2250a_4	*
545062   IGR2276a_1	*
553189   IGR2292a_1	*
570978   IGR3005a_1	*
571022   IGR3005a_2	*
576586   IGR3016a_1	*
577141   IGR3018a_2	*
577838   IGR3019a_2	*
578122   IGR3020a_1	*
579217   IGR3022a_1	*
579529   IGR3023a_1	*
579818   IGR3023a_3	*
582651   IGR3029a_1	*
582948   IGR3029a_2	*
583131   IGR3030a_1	*
587836   IGR3039a_1	*
590425   IGR3044a_1	*
590585   IGR3045a_1	*
594115   IGR3051a_1	*
594812   IGR3053a_1	*
598805   IGR3061a_1	*
601294   IGR3066a_1	*
608759   IGR3081a_1	*
610447   IGR3084a_1	*
611177   IGR3086a_1	BLOCK 7
613488   IGR3090a_1
616241   IGR3096a_1	BLOCK 8
616763   IGR3097a_1	*
617299   IGR3098a_1	*
626881   IGR3117a_1	*
633786   IGR3131a_1	*
635072   IGR3134a_1	*
637441   IGR3138a_1	BLOCK 8
648564   IGR3161a_1
649061   IGR3162a_1	BLOCK 9
649903   IGR3163a_1	*
657234   IGR3178a_1	*
662077   IGR3188a_1	*
662819   IGR3189a_2	*
676688   IGRX100a_1	BLOCK 9
683387   IGR3230a_1	BLOCK 10
686249   IGR3236a_1	*
692320   IGR3248a_1	*
718291   IGR3300a_2	*
730313   IGR3324a_1	*
731025   IGR3326a_1	*
738461   IGR3340a_1	BLOCK 10
871978   GENS021ex1_2	BLOCK 11
877571   GENS020ex3_3	*
877671   GENS020ex3_2	*
877809   GENS020ex3_1	*
890710   GENS020ex1_1	BLOCK 11
However it has been updated after the paper was published (posted on http://www.broad.mit.edu/humgen/IBD5/haplodata.html)

Usage

data(crohn)

Format

A data frame containing 387 rows and 212 columns

Source

MJ Daly, JD Rioux, SF Schaffner, TJ Hudson, ES Lander (2001) High-resolution haplotype structure in the human genome Nature Genetics 29:229-232